· Previous cancer treatment. People who’ve had certain types of chemotherapy and radiation therapy for other cancers have an increased risk of developing certain types of leukemia.
· Genetic disorders. Genetic abnormalities seem to play a role in the development of leukemia. Certain genetic disorders, such as Down syndrome, are associated with an increased risk of leukemia.
· Exposure to certain chemicals. Exposure to certain chemicals, such as benzene — which is found in gasoline and is used by the chemical industry — is linked to an increased risk of some kinds of leukemia.
· Smoking. Smoking cigarettes increases the risk of acute myelogenous leukemia.
· Family history of leukemia. If members of your family have been diagnosed with leukemia, your risk of the disease may be increased.
TYPES OF LEUKEMIA
· Acute lymphocytic leukemia (ALL). This is the most common type of leukemia in young children. ALL can also occur in adults.
· Acute myelogenous leukemia (AML). AML is a common type of leukemia. It occurs in children and adults. AML is the most common type of acute leukemia in adults.
· Chronic lymphocytic leukemia (CLL). With CLL, the most common chronic adult leukemia, you may feel well for years without needing treatment.
· Chronic myelogenous leukemia (CML). This type of leukemia mainly affects adults. A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.
· Other types. Other, rarer types of leukemia exist, including hairy cell leukemia, myelodysplastic syndromes and myeloproliferative disorders.
Doctors classify leukemia based on its speed of progression and the type of cells involved.
The first type of classification is by how fast the leukemia progresses
The second type of classification is by type of white blood cell affected:
· Lymphocytic leukemia. This type of leukemia affects the lymphoid cells (lymphocytes), which form lymphoid or lymphatic tissue. Lymphatic tissue makes up your immune system.
· Myelogenous (my-uh-LOHJ-uh-nus) leukemia. This type of leukemia affects the myeloid cells. Myeloid cells give rise to red blood cells, white blood cells and platelet-producing cell
· Fever or chills
· Persistent fatigue, weakness
· Frequent or severe infections
· Losing weight without trying
· Swollen lymph nodes, enlarged liver or spleen
· Easy bleeding or bruising
· Recurrent nosebleeds
· Tiny red spots in your skin (petechiae)
· Excessive sweating, especially at night
· Bone pain or tenderness
From: Mayo Clinic